Released in an ultra-limited first series of only 1,000 units, each bottle is individually numbered, reinforcing its exclusivity and rarity. A handwritten detail on the packaging adds a personal touch, reflecting scientific rigor and precision in selection. This deliberate approach highlights the uniqueness of the formula, positioning each bottle as a true collector’s item at the intersection of scientific excellence and refined exclusivity.

Skin cells are among the most energy-intensive cells due to their constant renewal cycle. This energy is produced within the mitochondria in the form of ATP (adenosine triphosphate), the essential fuel for all cellular activity.

With age and repeated external aggressions:

• Mitochondrial efficiency decreases

• ATP production declines

• Oxidative stress accumulates

These biological changes directly result in visible signs of skin fatigue: a dull complexion, loss of radiance, decreased vitality, and accelerated aging.

Born from Professor Jacques Proust’s vision to transform scientific knowledge on cellular aging into concrete, personalized, and accessible solutions, the Nescens cosmeceutical range is developed around the biology of aging to help extend the benefits of regenerative treatments into everyday skincare.

“Mitrochondrial dysfunction is now recognized as one of the hallmarks of aging. The decline in cellular energy production directly impacts skin’s biological functions, particularly its ability to renew and repair itself. Stimulating mitophagy and mitochondrial biogenesis therefore represents a new strategy to support skin longevity,” explains Professor Jacques Proust.

Each ingredient in the formulation is selected for a precise biological function. Far from decorative, they are all scientifically active contributors to cellular energy metabolism, mitochondrial performance, and skin vitality helping justify the positioning of a high-performance cosmeceutical formula.

RejuveNAD® (Helianthus Annuus Sprout Extract)

Contributes to increasing NAD+ levels and supports efficient mitochondrial electron transfer, playing a central role in cellular energy metabolism.

Niacinamide

Promotes the formation of NAD+, an essential cofactor in mitochondrial energy metabolism, while contributing to improved vitality and overall skin radiance.

Coenzyme Q10 (Ubiquinone)

A key component of the mitochondrial respiratory chain, directly involved in ATP synthesis and recognized for its antioxidant properties.

Resveratrol

Supports cellular energy pathways and helps protect mitochondria against oxidative stress.

Taurine & Green Tea Extract

Contribute to skin comfort, hydration, and antioxidant defense in stressful environmental conditions.